This territory has been very important in the history of Cantabria. First, because of the famous stonemasons of Trasmiera, temporary migrants to Castile. In the early 16th century several Cantabrian architects supervised the construction of the most important buildings of the time in Spain: Solórzano, Ruesga, Gil de Hontañón, Maza and Rasines were responsible for such works as the cathedrals of Salamanca, Segovia and Palencia.

Secondly, in the early 17th century Artillery Factories were established in Trasmiera (at Liérganes and La Cavada) which contributed to the maintenance of the Spanish empire through to the 19th century, and this in turn contributed to the development and significance of this area for over a century.

As for the artistic heritage of Trasmiera, the area is rich in 17th and 18th century casonas (noble homesteads); the area´s religious architecture is mostly 16th, 17th, and 18th century, although some churches retain their original medieval capital section. Fine altarpieces can be found in all of them, as in the late 16th century several workshops (at Limpias, Cudeyo and Siete Villas) were established in Trasmiera, attracting many master-craftsmen whose output was very plentiful.

The popular architecture of this district is interesting. Houses are either strung together in rows, or isolated, with whitewashed walls -but leaving bare the stonework on corners and surrounding windows- and well-built entrance arches of stone.